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John D. Cook

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DNA and Bessel functions
John · 2026-08-10 · via John D. Cook

I was reading a book on the history of the discovery of the structure of DNA [1] and was surprised by a few passing references to Bessel functions.

According to Claude,

When X-rays are diffracted by a helical structure, the resulting diffraction pattern breaks into a series of horizontal “layer lines.” Cochran, Crick, and Vand showed mathematically that the diffracted amplitude on the n-th layer line is proportional to a Bessel function of the first kind, order n:

Jn(2π r R)

where r is the radius of the helix and R is the distance out from the center (the meridian) in the diffraction pattern.

The citation for this paragraph is a paper from 1952 [2] that amazingly is behind a paywall.

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[1] Watson and Crick didn’t “discover DNA” as is commonly said. DNA was discovered in 1878. Watson and Crick discovered the structure of DNA in 1953.

[2] Cochran, W., Crick, F. H. C., & Vand, V. (1952). “The Structure of Synthetic Polypeptides. I. The Transform of Atoms on a Helix.” Acta Crystallographica, 5(5), 581–586.