$\newcommand{\dist}{\operatorname{dist}}$ In this paper we define the notion of a probabilistic neighborhood in spatial data: Let a set $P$ of $n$ points in $\mathbb{R}^d$, a query point $q \in \mathbb{R}^d$, a distance metric $\dist$, and a monotonically decreasing function $f : \mathbb{R}^+ \rightarrow [0,1]$ be given. Then a point $p \in P$ belongs to the probabilistic neighborhood $N(q, f)$ of $q$ with respect to $f$ with probability $f(\dist(p,q))$. We envision applications in facility location, sensor networks, and other scenarios where a connection between two entities becomes less likely with increasing distance. A straightforward query algorithm would determine a probabilistic neighborhood in $Θ(n\cdot d)$ time by probing each point in $P$. To answer the query in sublinear time for the planar case, we augment a quadtree suitably and design a corresponding query algorithm. Our theoretical analysis shows that -- for certain distributions of planar $P$ -- our algorithm answers a query in $O((|N(q,f)| + \sqrt{n})\log n)$ time with high probability (whp). This matches up to a logarithmic factor the cost induced by quadtree-based algorithms for deterministic queries and is asymptotically faster than the straightforward approach whenever $|N(q,f)| \in o(n / \log n)$. As practical proofs of concept we use two applications, one in the Euclidean and one in the hyperbolic plane. In particular, our results yield the first generator for random hyperbolic graphs with arbitrary temperatures in subquadratic time. Moreover, our experimental data show the usefulness of our algorithm even if the point distribution is unknown or not uniform: The running time savings over the pairwise probing approach constitute at least one order of magnitude already for a modest number of points and queries.