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NIST Sesame Reference Material Initiative – Call to Collaborate NIST/NIBIB Symposium on Medical Metrology and Standards for American Healthcare and Commerce NIST Receives New Patent for Microbe-Killing Water Heater Spotlight: How NIST Helps Make Sure the Fish You Catch Are Safe to Eat NIST Expands Its Library of ‘Chemical Fingerprints’ to Identify Unknown Substances SRM Story: SRM 1947a Great Lakes Fish Tissue SRM Story: SRMs 3672a and 3673a Organic Contaminants in Smokers’ and Nonsmokers’ Urine Space: The Final Frontier for Standards Securing Smart Speakers for Home Health Care: NIST Offers New Guidelines NIST’s ‘Living Reference Material’ Could Accelerate R&D of Lifesaving Biological Drugs NIST Awards Over $1.8 Million to Small Businesses Advancing AI, Semiconductors, Additive Manufacturing and More SRM Story: SRM 965c Glucose in Frozen Human Serum Second Seminar on Building an In-Space Circular Economy New NIST Reference Material to Strengthen Quality Control for Biological Drugs NIST Releases Trove of Genetic Data to Spur Cancer Research New NIST Research Grade Test Material to support mRNA therapeutics NIST Shares Preliminary Findings From Hurricane Maria Investigation New NIST Standard Helps Deliver the Right Dosage of Cancer-Fighting Drugs Second Series of Workshops on Measurements and Standards for Advanced Therapy NIST Researcher Addresses London Healthcare Innovation Forum NIST Releases Reference Material to Aid Gut Microbiome Research NIST Researchers Develop Material for Measuring Arsenic in Shellfish 2025 NIST Workshop on Rapid Microbial Testing Methods An SRM for Accuracy in Electrolyte Panel Clinical Tests Study Highlights Need for Standardized Measurement Methods in Gene Therapy NIST Develops Genetic Material for Validating H5N1 Bird Flu Diagnostic Tests PFAS Found in Firefighter Gloves, Hoods and Wildland Gear AI and Flow Cytometry Workshop Genome Editing Consortium Workshop Social Spotlight: Engineered Cells as a Shoebox
Spotlight: Researchers Develop Quality Control Tool for B...
Sarah Henderson · 2026-08-14 · via News and Events Feed by Topic

Researcher working in lab with safety glasses and gloves

NIST researcher Megan Cleveland was part of a team that developed a nonhazardous, synthetic genetic material that will aid in the development of new diagnostic tests for the H5N1 virus, in collaboration with the U.S. Centers for Disease Control and Prevention.

Credit: A. Boss/NIST

NIST researchers have developed a reference material for H5N1 avian influenza or bird flu. Manufacturers in the biotech and pharmaceutical industries can use the reference material to safely assess their diagnostic tests, such as PCR assays, for avian influenza.

Polymerase chain reaction (PCR) assays are a fast, lab method used to amplify genetic material, such as DNA or RNA, in a sample. They also serve as a helpful tool for detecting infectious diseases or viruses, especially during a pandemic.

This reference material will help calibrate labs and manufacturers’ PCR assays to make sure they are precise and accurate. The material is an upgraded version of a test material released last year.

Released August 14, 2026, Updated September 18, 2026