We propose a decoupled 3D scene generation framework called SceneMaker in this work. Due to the lack of sufficient open-set de-occlusion and pose estimation priors, existing methods struggle to simultaneously produce high-quality geometry and accurate poses under severe occlusion and open-set settings. To address these issues, we first decouple the de-occlusion model from 3D object generation, and enhance it by leveraging image datasets and collected de-occlusion datasets for much more diverse open-set occlusion patterns. Then, we propose a unified pose estimation model that integrates global and local mechanisms for both self-attention and cross-attention to improve accuracy. Besides, we construct an open-set 3D scene dataset to further extend the generalization of the pose estimation model. Comprehensive experiments demonstrate the superiority of our decoupled framework on both indoor and open-set scenes. Our codes and datasets is released at https://idea-research.github.io/SceneMaker/.