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cs.AI updates on arXiv.org

Policy Split: Incentivizing Dual-Mode Exploration in LLM Reinforcement with Dual-Mode Entropy Regularization METER: Evaluating Multi-Level Contextual Causal Reasoning in Large Language Models Think Before you Write: QA-Guided Reasoning for Character Descriptions in Books METRO: Towards Strategy Induction from Expert Dialogue Transcripts for Non-collaborative Dialogues Retrieval as Generation: A Unified Framework with Self-Triggered Information Planning Do LLMs Know Tool Irrelevance? Demystifying Structural Alignment Bias in Tool Invocations Enhancing Multimodal Large Language Models for Ancient Chinese Character Evolution Analysis via Glyph-Driven Fine-Tuning Exploring Knowledge Conflicts for Faithful LLM Reasoning: Benchmark and Method CocoaBench: Evaluating Unified Digital Agents in the Wild MathAgent: Adversarial Evolution of Constraint Graphs for Mathematical Reasoning Data Synthesis Efficient Training for Cross-lingual Speech Language Models Shared Emotion Geometry Across Small Language Models: A Cross-Architecture Study of Representation, Behavior, and Methodological Confounds A Systematic Analysis of the Impact of Persona Steering on LLM Capabilities Uncertainty-Aware Web-Conditioned Scientific Fact-Checking When Valid Signals Fail: Regime Boundaries Between LLM Features and RL Trading Policies When Verification Fails: How Compositionally Infeasible Claims Escape Rejection Mem$^2$Evolve: Towards Self-Evolving Agents via Co-Evolutionary Capability Expansion and Experience Distillation AOP-Smart: A RAG-Enhanced Large Language Model Framework for Adverse Outcome Pathway Analysis Advancing Polish Language Modeling through Tokenizer Optimization in the Bielik v3 7B and 11B Series TInR: Exploring Tool-Internalized Reasoning in Large Language Models Do BERT Embeddings Encode Narrative Dimensions? A Token-Level Probing Analysis of Time, Space, Causality, and Character in Fiction Generating Multiple-Choice Knowledge Questions with Interpretable Difficulty Estimation using Knowledge Graphs and Large Language Models Deep-Reporter: Deep Research for Grounded Multimodal Long-Form Generation Too Nice to Tell the Truth: Quantifying Agreeableness-Driven Sycophancy in Role-Playing Language Models Learning and Enforcing Context-Sensitive Control for LLMs Efficient Process Reward Modeling via Contrastive Mutual Information Computational Lesions in Multilingual Language Models Separate Shared and Language-specific Brain Alignment Bridging Linguistic Gaps: Cross-Lingual Mapping in Pre-Training and Dataset for Enhanced Multilingual LLM Performance Early Decisions Matter: Proximity Bias and Initial Trajectory Shaping in Non-Autoregressive Diffusion Language Models LLMs Should Incorporate Explicit Mechanisms for Human Empathy
Large Language Models Predict Functional Outcomes after A...
2026-01-18 · via cs.AI updates on arXiv.org

Accurate prediction of functional outcomes after acute ischemic stroke can inform clinical decision-making and resource allocation. Prior work on modified Rankin Scale (mRS) prediction has relied primarily on structured variables (e.g., age, NIHSS) and conventional machine learning. The ability of large language models (LLMs) to infer future mRS scores directly from routine admission notes remains largely unexplored. We evaluated encoder (BERT, NYUTron) and generative (Llama-3.1-8B, MedGemma-4B) LLMs, in both frozen and fine-tuned settings, for discharge and 90-day mRS prediction using a large, real-world stroke registry. The discharge outcome dataset included 9,485 History and Physical notes and the 90-day outcome dataset included 1,898 notes from the NYU Langone Get With The Guidelines-Stroke registry (2016-2025). Data were temporally split with the most recent 12 months held out for testing. Performance was assessed using exact (7-class) mRS accuracy and binary functional outcome (mRS 0-2 vs. 3-6) accuracy and compared against established structured-data baselines incorporating NIHSS and age. Fine-tuned Llama achieved the highest performance, with 90-day exact mRS accuracy of 33.9% [95% CI, 27.9-39.9%] and binary accuracy of 76.3% [95% CI, 70.7-81.9%]. Discharge performance reached 42.0% [95% CI, 39.0-45.0%] exact accuracy and 75.0% [95% CI, 72.4-77.6%] binary accuracy. For 90-day prediction, Llama performed comparably to structured-data baselines. Fine-tuned LLMs can predict post-stroke functional outcomes from admission notes alone, achieving performance comparable to models requiring structured variable abstraction. Our findings support the development of text-based prognostic tools that integrate seamlessly into clinical workflows without manual data extraction.