Photorealistic Codec Avatars (PCA), which generate high-fidelity human face renderings, are increasingly being used in Virtual Reality (VR) environments to enable immersive communication and interaction through deep learning-based generative models. However, these models impose significant computational demands, making real-time inference challenging on resource-constrained VR devices such as head-mounted displays, where latency and power efficiency are critical. To address this challenge, we propose an efficient post-training quantization (PTQ) method tailored for Codec Avatar models, enabling low-precision execution without compromising output quality. In addition, we design a custom hardware accelerator that can be integrated into the system-on-chip of VR devices to further enhance processing efficiency. Building on these components, we introduce ESCA, a full-stack optimization framework that accelerates PCA inference on edge VR platforms. Experimental results demonstrate that ESCA boosts FovVideoVDP quality scores by up to $+0.39$ over the best 4-bit baseline, delivers up to $3.36\times$ latency reduction, and sustains a rendering rate of 100 frames per second in end-to-end tests, satisfying real-time VR requirements. These results demonstrate the feasibility of deploying high-fidelity codec avatars on resource-constrained devices, opening the door to more immersive and portable VR experiences.