Krista Satterthwaite

Senior vice president and general manager, Compute, HPE

“HPE Compute Scale-up Server 3250 raises the bar for business-critical infrastructure,” said Krista Satterthwaite, senior vice president and general manager, Compute at HPE. “Designed for complex business applications like enterprise resource planning and customer relationship management systems, this system helps customers in ways competitive offerings cannot –  allowing them to run faster transactions, gain insights in real time, and support analytics without slowing down business. With simpler operations, always-on reliability, and chip-to-cloud security – we’re redefining what scale looks like for workloads with zero-tolerance downtime.”

The server scales modularly to meet the rising demands of real-time analytics and high-velocity transactions. Available from a minimum of four sockets, up to 16 – and supporting up to 64 TB of DDR5 memory – the server enables customers to run financial services applications, databases, and systems of record. A dedicated external node controller in HPE Compute Scale-up Server 3250 offers a performance boost that is 100 times² faster than Ethernet used in scale-out deployments. This is HPE’s first scale-up server powered by Intel Xeon 6 processors and features a modular architecture well-suited for heavy compute and emerging agentic AI workloads.

“Our collaboration with HPE continues to blaze the trail for mission‑critical, in‑memory computing,” said Kevork Kechichian, executive vice president and general manager, Data Center Group at Intel. “The HPE Compute Scale‑Up Server 3250, powered by Intel Xeon 6 processors, brings together exceptional compute density, scalability, and reliability to help enterprises run their most critical data‑intensive workloads.”

Multi-layered security and resiliencyBuilt-in protection for HPE Compute Scale-up Server 3250 is available through HPE Integrated Lights Out (iLO) and spans every layer – from the chip to the cloud – as well as the entire lifecycle of the server. HPE iLO establishes a silicon root of trust through a dedicated security processor and validated firmware, which safeguards against future threats with post-quantum cryptography. Resiliency features of the HPE Compute Scale-up Server 3250 include advanced memory error detection and correction, as well as memory healing and deconfiguration. Additionally, the server is designed for fault-tolerant uptime, delivering the highest availability for critical business workloads.

HPE leadership for RISE with SAP-certified serversHPE Compute Scale-up Server 3250 is the successor to the Intel-based HPE Scale-up Server 3200. HPE was recently named as a leader in the IDC MarketScape: Worldwide SAP HANA Certified Servers Appliances 2026 Vendor Assessment³. HPE’s long-standing collaboration with SAP and sustained engineering investment has positioned HPE as a leading provider of RISE with SAP-certified servers. HPE Compute Scale-up Server 3250 builds on that reputation with record-setting benchmark performance for large, in-memory configurations.

AvailabilityThe HPE Compute Scale-up Server 3250 is available now.

This server can be acquired through HPE Financial Service’s 90/9 Advantage program that offers no payments for 90 days and an additional 9 months at one percent.

Additional Resources