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Theoretical Limits of Language Model Alignment $f$-Divergence Regularized RLHF: Two Tales of Sampling and Unified Analyses A Unified Measure-Theoretic View of Diffusion, Score-Based, and Flow Matching Generative Models When Can Voting Help, Hurt, or Change Course? Exact Structure of Binary Test-Time Aggregation When Semantic Communication Meets Queueing: Cross-Layer Latency and Task Fidelity Optimization Convexity in Disguise: A Theoretical Framework for Nonconvex Low-Rank Matrix Estimation Conditional Diffusion Under Linear Constraints: Langevin Mixing and Information-Theoretic Guarantees Sharp Capacity Thresholds in Linear Associative Memory: From Winner-Take-All to Listwise Retrieval Expert Routing for Communication-Efficient MoE via Finite Expert Banks Contextual Memory-Enhanced Source Coding for Low-SNR Communications Realizable Bayes-Consistency for General Metric Losses Leveraging Code Automorphisms for Improved Syndrome-Based Neural Decoding A Hierarchical Sampling Framework for bounding the Generalization Error of Federated Learning Dueling DDQN-Based Adaptive Multi-Objective Handover Optimization for LEO Satellite Networks The Causal Description Gap: Information-Theoretic Separations Across Pearl's Hierarchy Optimization of CV-QKD Under Practical Constraints Benchmarking Wireless Representations: High-Dimensional vs. Compressed Embeddings for Efficiency and Robustness Real-Time Text Transmission via LLM-Based Entropy Coding over Fixed-Rate Channels SwiftChannel: Algorithm-Hardware Co-Design for Deep Learning-Based 5G Channel Estimation Evolving Token Communication with Parametric Memory Network Remote Action Generation: Remote Control with Minimal Communication The (Marginal) Value of a Search Ad: An Online Causal Framework for Repeated Second-price Auctions Stabilizing Private LASSO under Heterogeneous Covariates via Anisotropic Objective Perturbation Linear-Readout Floors and Threshold Recovery in Computation in Superposition Soft Graph Diffusion Transformer for MIMO Detection Hierarchical Federated Learning for Networked AI: From Communication Saving to Architecture-Aware Design Exponential families from a single KL identity MIFair: A Mutual-Information Framework for Intersectionality and Multiclass Fairness Diffusion-OAMP for Joint Image Compression and Wireless Transmission Decoupled Descent: Exact Test Error Tracking Via Approximate Message Passing
Noise-immune and AI-enhanced DNA storage via adaptive par...
Zimu Li, Bingyi Liu, Lei Zhao, Qian Zhang, Yang Liu, Jun Liu, Ke · 2026-01-23 · via cs.IT updates on arXiv.org

Encoding digital information into DNA sequences offers an attractive potential solution for storing rapidly growing data under the information age and the rise of artificial intelligence. However, practical implementations of DNA storage are constrained by errors introduced during synthesis, preservation, and sequencing processes, and traditional error-correcting codes remain vulnerable to noise levels that exceed predefined thresholds. Here, we developed a Partitioning-mapping with Jump-rotating (PJ) encoding scheme, which exhibits exceptional noise resilience. PJ removes cross-strand information dependencies so that strand loss manifests as localized gaps rather than catastrophic file failure. It prioritizes file decodability under arbitrary noise conditions and leverages AI-based inference to enable controllable recovery of digital information. For the intra-strand encoding, we develop a jump-rotating strategy that relaxes sequence constraints relative to conventional rotating codes and provides tunable information density via an adjustable jump length. Based on this encoding architecture, the original file information can always be decoded and recovered under any strand loss ratio, with fidelity degrading smoothly as damage increases. We demonstrate that original files can be effectively recovered even with 10% strand loss, and machine learning datasets stored under these conditions retain their classification performance. Experiments further confirmed that PJ successfully decodes image files after extreme environmental disturbance using accelerated aging and high-intensity X-ray irradiation. By eliminating reliance on prior error probabilities, PJ establishes a general framework for robust, archival DNA storage capable of withstanding the rigorous conditions of real-world preservation.