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cs.IT updates on arXiv.org

Theoretical Limits of Language Model Alignment $f$-Divergence Regularized RLHF: Two Tales of Sampling and Unified Analyses A Unified Measure-Theoretic View of Diffusion, Score-Based, and Flow Matching Generative Models When Can Voting Help, Hurt, or Change Course? Exact Structure of Binary Test-Time Aggregation When Semantic Communication Meets Queueing: Cross-Layer Latency and Task Fidelity Optimization Convexity in Disguise: A Theoretical Framework for Nonconvex Low-Rank Matrix Estimation Conditional Diffusion Under Linear Constraints: Langevin Mixing and Information-Theoretic Guarantees Sharp Capacity Thresholds in Linear Associative Memory: From Winner-Take-All to Listwise Retrieval Expert Routing for Communication-Efficient MoE via Finite Expert Banks Contextual Memory-Enhanced Source Coding for Low-SNR Communications Realizable Bayes-Consistency for General Metric Losses Leveraging Code Automorphisms for Improved Syndrome-Based Neural Decoding A Hierarchical Sampling Framework for bounding the Generalization Error of Federated Learning Dueling DDQN-Based Adaptive Multi-Objective Handover Optimization for LEO Satellite Networks The Causal Description Gap: Information-Theoretic Separations Across Pearl's Hierarchy Optimization of CV-QKD Under Practical Constraints Benchmarking Wireless Representations: High-Dimensional vs. Compressed Embeddings for Efficiency and Robustness Real-Time Text Transmission via LLM-Based Entropy Coding over Fixed-Rate Channels SwiftChannel: Algorithm-Hardware Co-Design for Deep Learning-Based 5G Channel Estimation Evolving Token Communication with Parametric Memory Network Remote Action Generation: Remote Control with Minimal Communication The (Marginal) Value of a Search Ad: An Online Causal Framework for Repeated Second-price Auctions Stabilizing Private LASSO under Heterogeneous Covariates via Anisotropic Objective Perturbation Linear-Readout Floors and Threshold Recovery in Computation in Superposition Soft Graph Diffusion Transformer for MIMO Detection Hierarchical Federated Learning for Networked AI: From Communication Saving to Architecture-Aware Design Exponential families from a single KL identity MIFair: A Mutual-Information Framework for Intersectionality and Multiclass Fairness Diffusion-OAMP for Joint Image Compression and Wireless Transmission Decoupled Descent: Exact Test Error Tracking Via Approximate Message Passing
DNA data storage, sequencing data-carrying DNA
Jasmine Quah, Omer Sella, Thomas Heinis · 2022-05-11 · via cs.IT updates on arXiv.org

DNA is a leading candidate as the next archival storage media due to its density, durability and sustainability. To read (and write) data DNA storage exploits technology that has been developed over decades to sequence naturally occurring DNA in the life sciences. To achieve higher accuracy for previously unseen, biological DNA, sequencing relies on extending and training deep machine learning models known as basecallers. This growth in model complexity requires substantial resources, both computational and data sets. It also eliminates the possibility of a compact read head for DNA as a storage medium. We argue that we need to depart from blindly using sequencing models from the life sciences for DNA data storage. The difference is striking: for life science applications we have no control over the DNA, however, in the case of DNA data storage, we control how it is written, as well as the particular write head. More specifically, data-carrying DNA can be modulated and embedded with alignment markers and error correcting codes to guarantee higher fidelity and to carry out some of the work that the machine learning models perform. In this paper, we study accuracy trade-offs between deep model size and error correcting codes. We show that, starting with a model size of 107MB, the reduced accuracy from model compression can be compensated by using simple error correcting codes in the DNA sequences. In our experiments, we show that a substantial reduction in the size of the model does not incur an undue penalty for the error correcting codes used, therefore paving the way for portable data-carrying DNA read head. Crucially, we show that through the joint use of model compression and error correcting codes, we achieve a higher read accuracy than without compression and error correction codes.