Soft noncoherent detection, which relies on calculating the \textit{a posteriori} probabilities (APPs) of the bits transmitted with no channel estimation, is imperative for achieving excellent detection performance in high-dimensional wireless communications. In this paper, a high-performance belief propagation (BP)-based soft multiple-symbol differential detection (MSDD) framework, dubbed BP-MSDD, is proposed with its illustrative application in differential space-time block-code (DSTBC)-aided ultra-wideband impulse radio (UWB-IR) systems. Firstly, we revisit the signal sampling with the aid of a trellis structure and decompose the trellis into multiple subtrellises. Furthermore, we derive an APP calculation algorithm, in which the forward-and-backward message passing mechanism of BP operates on the subtrellises. The proposed BP-MSDD is capable of significantly outperforming the conventional hard-decision MSDDs. However, the computational complexity of the BP-MSDD increases exponentially with the number of MSDD trellis states. To circumvent this excessive complexity for practical implementations, we reformulate the BP-MSDD, and additionally propose a Viterbi algorithm (VA)-based hard-decision MSDD (VA-HMSDD) and a VA-based soft-decision MSDD (VA-SMSDD). Moreover, both the proposed BP-MSDD and VA-SMSDD can be exploited in conjunction with soft channel decoding to obtain powerful iterative detection and decoding based receivers. Simulation results demonstrate the effectiveness of the proposed algorithms in DSTBC-aided UWB-IR systems.