This paper investigates the information rate loss in analog channels when the sampler is designed to operate independent of the instantaneous channel occupancy. Specifically, a multiband linear time-invariant Gaussian channel under universal sub-Nyquist sampling is considered. The entire channel bandwidth is divided into $n$ subbands of equal bandwidth. At each time only $k$ constant-gain subbands are active, where the instantaneous subband occupancy is not known at the receiver and the sampler. We study the information loss through a capacity loss metric, that is, the capacity gap caused by the lack of instantaneous subband occupancy information. We characterize the minimax capacity loss for the entire sub-Nyquist rate regime, provided that the number $n$ of subbands and the SNR are both large. The minimax limits depend almost solely on the band sparsity factor and the undersampling factor, modulo some residual terms that vanish as $n$ and SNR grow. Our results highlight the power of randomized sampling methods (i.e. the samplers that consist of random periodic modulation and low-pass filters), which are able to approach the minimax capacity loss with exponentially high probability.