This paper proposes an integrated sensing and communication (ISAC)-enabled grant-free uplink framework based on artificial-path delay modulation. A grant-free user equipment (g-UE) conveys uplink information by modulating the delay of a controllable artificial path derived from the scheduled downlink waveform. In contrast to conventional superposition-based schemes with successive interference cancellation, the proposed method enables uplink-downlink coexistence in the delay-sensing domain. By introducing a single weak artificial path confined within the cyclic prefix (CP), the g-UE allows the access point (AP) to decode uplink symbols from CSI perturbations while causing only limited degradation to the scheduled user equipment (s-UE) in the downlink. To support reliable finite-alphabet delay detection under unknown path gain and off-grid leakage, we develop a baseline delay calibration procedure and a normalized matched-filter detector. Results show that reflection power determines the reliability trade-off between the g-UE and the s-UE, whereas the delay step mainly controls the g-UE reliability-efficiency trade-off with little additional impact on the downlink s-UE. Even with an artificial path 15 dB weaker than the scheduled downlink signal, the g-UE achieves lower BER than the s-UE at an effective modulation order of 16-QAM. The proposed framework thus offers a low-complexity, SIC-free, and downlink-friendly solution for grant-free uplink in ISAC systems.