In this paper, an intelligent reflecting surface (IRS)-aided large-scale MIMO system is investigated in which constant envelope precoding (CEP) is utilized at each base station (BS). It is both cost-effective and energy-efficient to implement CEP in a large-scale antenna array. We aim to optimize the discrete phase shifts at both the BS and the IRS to minimize the sum power of multi-user interference (MUI) in the system via our proposed three algorithms. For the sake of simplicity, a simple single-cell scenario is considered, where the optimization of the BS and IRS phase shifts is solved by a low-complexity trellis-based algorithm. Then, this algorithm is extended to a multi-cell scenario, where the precoding operation in each BS is performed individually. With the aid of stochastic optimization method, a low-overhead trellis-based solution is proposed which has better performance than the first one. Finally, we solve the optimization problem via the semi-definite relaxation (SDR) scheme, to serve as a performance benchmark for the proposed algorithms. Meanwhile, interference and complexity analysis is provided for the proposed algorithms. Numerical results demonstrate that while the performance of the trellis-based algorithms is negligibly lower than that of the continuous-phase SDR-based solution, the computational complexity and the implementation cost of the former is much lower than the latter, which is appealing for practical applications.