惯性聚合 高效追踪和阅读你感兴趣的博客、新闻、科技资讯
阅读原文 在惯性聚合中打开

推荐订阅源

罗磊的独立博客
Martin Fowler
Martin Fowler
J
Java Code Geeks
The GitHub Blog
The GitHub Blog
C
Check Point Blog
H
Help Net Security
Google DeepMind News
Google DeepMind News
人人都是产品经理
人人都是产品经理
博客园 - 聂微东
P
Proofpoint News Feed
V
Visual Studio Blog
Stack Overflow Blog
Stack Overflow Blog
雷峰网
雷峰网
freeCodeCamp Programming Tutorials: Python, JavaScript, Git & More
Vercel News
Vercel News
S
SegmentFault 最新的问题
L
LangChain Blog
Cyber Security Advisories - MS-ISAC
Cyber Security Advisories - MS-ISAC
The Cloudflare Blog
Hugging Face - Blog
Hugging Face - Blog
有赞技术团队
有赞技术团队
博客园_首页
小众软件
小众软件
aimingoo的专栏
aimingoo的专栏

math.ST updates on arXiv.org

What is Learnable in Valiant's Theory of the Learnable? Learning Perturbations to Extrapolate Your LLM Byzantine-Robust Distributed Sparse Learning Revisited The Sample Complexity of Multiple Change Point Identification under Bandit Feedback A proximal gradient algorithm for composite log-concave sampling Model-based Bootstrap of Controlled Markov Chains Approximation of Maximally Monotone Operators : A Graph Convergence Perspective Posterior Contraction Rates for Sparse Kolmogorov-Arnold Networks in Anisotropic Besov Spaces MIST: Reliable Streaming Decision Trees for Online Class-Incremental Learning via McDiarmid Bound A Spectral Framework for Closed-Form Relative Density Estimation Fast Rates for Offline Contextual Bandits with Forward-KL Regularization under Single-Policy Concentrability Higher-Order Equilibrium Tracking for EM-Compressible Online Estimation Scaling Limits of Long-Context Transformers A Note on Non-Negative $L_1$-Approximating Polynomials Susceptibilities and Patterning: A Primer on Linear Response in Bayesian Learning Linear Response Estimators for Singular Statistical Models Statistical inference with belief functions: A survey Robust stochastic first order methods in heavy-tailed noise via medoid mini-batch gradient sampling Every Feedforward Neural Network Definable in an o-Minimal Structure Has Finite Sample Complexity Adaptive auditing of AI systems with anytime-valid guarantees Locally Near Optimal Piecewise Linear Regression in High Dimensions via Difference of Max-Affine Functions Risk-Controlled Post-Processing of Decision Policies Covariate Balancing and Riesz Regression Should Be Guided by the Neyman Orthogonal Score in Debiased Machine Learning A Unified Pair-GRPO Family: From Implicit to Explicit Preference Constraints for Stable and General RL Alignment Time-Inhomogeneous Preconditioned Langevin Dynamics A Fine-Grained Understanding of Uniform Convergence for Halfspaces CITE: Anytime-Valid Statistical Inference in LLM Self-Consistency Ratio-based Loss Functions Optimal Confidence Band for Kernel Gradient Flow Estimator A renormalization-group inspired lattice-based framework for piecewise generalized linear models
Estimation and Inference of the Win Ratio for Two Hierarc...
Yi Liu, Huiman Barnhart, Sean O'Brien, Yuliya Lokhnygina, Roland · 2026-02-14 · via math.ST updates on arXiv.org

The win ratio (WR) is a widely used metric to compare treatments in randomized clinical trials with hierarchically ordered endpoints. Counting-based approaches, such as Pocock's algorithm, are the standard for WR estimation. However, this algorithm treats participants with censored or missing data inadequately, which may lead to biased and inefficient estimates, particularly in the presence of heterogeneous censoring or missing data between treatment groups. Although recent extensions have addressed some of these limitations for hierarchical time-to-event endpoints, no existing methods -- aside from the computationally intensive multiple imputation approach -- can accommodate settings that include non-survival endpoints that are subject to missing data. In this paper, we propose a simple nonparametric maximum likelihood estimator (NPMLE) of WR for two hierarchical endpoints that are subject to censoring and missing data. Our method uses all observed data, avoids strong parametric assumptions, and comes with a closed-form asymptotic variance estimator. We demonstrate its performance using simulation studies and two data examples, based on the HEART-FID and ISCHEMIA trials. The proposed method provides a consistent estimator, improves estimation efficiency, and is robust under non-informative censoring and missing at random (MAR) assumptions, offering a flexible alternative to existing WR estimation methods. A user-friendly R package, WinRS, is available to facilitate implementation.