A common assumption when modeling queuing systems is that arrivals behave like a Poisson process with constant parameter. In practice, however, call arrivals are often observed to be significantly overdispersed. This motivates that in this paper we consider a mixed Poisson arrival process with arrival rates that are resampled every $N^{a}$ time units, where $a> 0$ and $N$ a scaling parameter. In the first part of the paper we analyse the asymptotic tail distribution of this doubly stochastic arrival process. That is, for large $N$ and i.i.d. arrival rates $X_1, \dots, X_N$, we focus on the evaluation of $P_N(A)$, the probability that the scaled number of arrivals exceeds $NA$. Relying on elementary techniques, we derive the exact asymptotics of $P_N(A)$: For $a< \frac{1}{3}$ and $a > 3$ we identify (in closed-form) a function $\tilde{P}_N(A)$ such that $P_N(A) / P_N(A)$ tends to $1$ as $N \to \infty$. For $a \in [\frac{1}{3},\frac{1}{2})$ and $a\in [2, 3)$ we find a partial solution in terms of an asymptotic lower bound. For the special case that the $X_i$s are gamma distributed, we establish the exact asymptotics across all $a> 0$. In addition, we set up an asymptotically efficient importance sampling procedure that produces reliable estimates at low computational cost. The second part of the paper considers an infinite-server queue assumed to be fed by such a mixed Poisson arrival process. Applying a scaling similar to the one in the definition of $P_N(A)$, we focus on the asymptotics of the probability that the number of clients in the system exceeds $NA$. The resulting approximations can be useful in the context of staffing. Our numerical experiments show that, astoundingly, the required staffing level can actually decrease when service times are more variable.