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Visibility in the Boolean Model on Harmonic Manifolds Global estimates on the Brenier map Geodesics and Wandering Exponents in Brochette First-Passage Percolation State-dependent inverse-subordinator time changes of regenerative processes: Excursion structure and multiscale occupation-time limits Randomly twisted transfer operators and singular values statistics Generalized Bessel-Dunkl diffusions An almost sure invariance principle for the Takagi-van der Waerden class functions Central limit theorems for high dimensional lattice polytopes: cosmological polytopes Convergence rate estimates for semigroups and heat kernels associated with resistance forms Second-order Poincaré inequalities and localization on the Poisson space Maximum Probability of Independence in Transitive Matroids On global solutions to the semidiscrete stochastic heat equation The Poisson Tail Conjecture for primes in short intervals A Complete Spectral Analysis of the CEV Operator with Applications to Arbitrage Holographic functions and neural networks From Betting to Empirical Bernstein LIL Concentration of General Stochastic Approximation Under Heavy-Tailed Markovian Noise Pointwise Generalization in Deep Neural Networks Bayesian Latent Space Models for Graphs Are Misspecified: Toward Robust Inference via Generalized Posteriors Wasserstein bounds for denoising diffusion probabilistic models via the Föllmer process A note on connections between the Föllmer process and the denoising diffusion probabilistic model Simple Approximation and Derivative Free Inference-Time Scaling for Diffusion Models via Sequential Monte Carlo on Path Measures Diffusion-Based Stochastic Operator Networks for Uncertainty Quantification in Stochastic Partial Differential Equations A Fourier perspective on the learning dynamics of neural networks: from sample complexities to mechanistic insights Propagation of Chaos in Contextual Flow Maps Dimension-Uniform Discretization Analysis of Preconditioned Annealed Langevin Dynamics for Multimodal Gaussian Mixtures $α$-TCAV: A Unified Framework for Testing with Concept Activation Vectors Scaling Laws from Sequential Feature Recovery: A Solvable Hierarchical Model On the Limits of Latent Reuse in Diffusion Models State-of-art minibatches via novel DPP kernels: discretization, wavelets, and rough objectives
Coalescent-based species tree estimation: a stochastic Fa...
Gautam Dasarathy, Elchanan Mossel, Robert Nowak, Sebastien Roch · 2017-07-14 · via math.PR updates on arXiv.org

The reconstruction of a species phylogeny from genomic data faces two significant hurdles: 1) the trees describing the evolution of each individual gene--i.e., the gene trees--may differ from the species phylogeny and 2) the molecular sequences corresponding to each gene often provide limited information about the gene trees themselves. In this paper we consider an approach to species tree reconstruction that addresses both these hurdles. Specifically, we propose an algorithm for phylogeny reconstruction under the multispecies coalescent model with a standard model of site substitution. The multispecies coalescent is commonly used to model gene tree discordance due to incomplete lineage sorting, a well-studied population-genetic effect. In previous work, an information-theoretic trade-off was derived in this context between the number of loci, $m$, needed for an accurate reconstruction and the length of the locus sequences, $k$. It was shown that to reconstruct an internal branch of length $f$, one needs $m$ to be of the order of $1/[f^{2} \sqrt{k}]$. That previous result was obtained under the molecular clock assumption, i.e., under the assumption that mutation rates (as well as population sizes) are constant across the species phylogeny. Here we generalize this result beyond the restrictive molecular clock assumption, and obtain a new reconstruction algorithm that has the same data requirement (up to log factors). Our main contribution is a novel reduction to the molecular clock case under the multispecies coalescent. As a corollary, we also obtain a new identifiability result of independent interest: for any species tree with $n \geq 3$ species, the rooted species tree can be identified from the distribution of its unrooted weighted gene trees even in the absence of a molecular clock.