A Heffter array over an additive group $G$ is any partially filled array $A$ satisfying that: (1) each one of its rows and columns sum to zero in $G$, and (2) if $i\in G\setminus\{0\}$, then either $i$ or $-i$ appears exactly once in $A$. In this paper, this notion is naturally generalized to that of $\mathcal{B}$-Heffter array over a partial loop, where $\mathcal{B}$ is a set of block-sum polynomials over an affine $1$-design on the set of entries in $A$.