A 0/1-polytope is the convex hull of a subset $V\subseteq \{0,1\}^n$. A celebrated conjecture of Mihail and Vazirani asserts that the graph of every 0/1-polytope has edge-expansion at least 1. In this paper, we show that typical 0/1-polytopes have significantly stronger expansion. Specifically, if $V$ is formed by sampling each vertex of $\{0,1\}^n$ independently with constant probability $p$, then with high probability the edge-expansion is $Θ(n)$ for $p \in (1/2, 1)$, and $n^{Θ(\log \log n)}$ for $p \in (0, 1/2)$. This improves the previously best known bound $Ω(1)$ due to Ferber, Krivelevich, Sales and Samotij.