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Adaptive multi-fidelity optimization with fast learning rates Enhancing AI and Dynamical Subseasonal Forecasts with Probabilistic Bias Correction Sample Complexity Bounds for Stochastic Shortest Path with a Generative Model The Harder Path: Last Iterate Convergence for Uncoupled Learning in Zero-Sum Games with Bandit Feedback Stylistic-STORM (ST-STORM) : Perceiving the Semantic Nature of Appearance Collective Kernel EFT for Pre-activation ResNets PRIM-cipal components analysis One-Shot Generative Flows: Existence and Obstructions Structural interpretability in SVMs with truncated orthogonal polynomial kernels Amortized Optimal Transport from Sliced Potentials MinShap: A Modified Shapley Value Approach for Feature Selection Unsupervised feature selection using Bayesian Tucker decomposition Multi-User mmWave Beam and Rate Adaptation via Combinatorial Satisficing Bandits Best of both worlds: Stochastic & adversarial best-arm identification Scalable Model-Based Clustering with Sequential Monte Carlo Expert-Guided Class-Conditional Goodness-of-Fit Scores for Interpretable Classification with Informative Missingness: An Application to Seismic Monitoring Lightweight Geometric Adaptation for Training Physics-Informed Neural Networks Gating Enables Curvature: A Geometric Expressivity Gap in Attention Zeroth-Order Optimization at the Edge of Stability Differentially Private Conformal Prediction CLion: Efficient Cautious Lion Optimizer with Enhanced Generalization Generative Augmented Inference Improving Machine Learning Performance with Synthetic Augmentation PAC-MCTS: Bias-Aware Pruning for Robust LLM-Guided Search and Planning Path-Sampled Integrated Gradients Heat and Matérn Kernels on Matchings Doubly Outlier-Robust Online Infinite Hidden Markov Model Momentum Further Constrains Sharpness at the Edge of Stochastic Stability Multistage Conditional Compositional Optimization BOAT: Navigating the Sea of In Silico Predictors for Antibody Design via Multi-Objective Bayesian Optimization
Net benefit, calibration, threshold selection, and traini...
Stephen R. Pfohl, Yizhe Xu, Agata Foryciarz, Nikolaos Ignatiadis · 2022-02-04 · via stat.ML updates on arXiv.org

A growing body of work uses the paradigm of algorithmic fairness to frame the development of techniques to anticipate and proactively mitigate the introduction or exacerbation of health inequities that may follow from the use of model-guided decision-making. We evaluate the interplay between measures of model performance, fairness, and the expected utility of decision-making to offer practical recommendations for the operationalization of algorithmic fairness principles for the development and evaluation of predictive models in healthcare. We conduct an empirical case-study via development of models to estimate the ten-year risk of atherosclerotic cardiovascular disease to inform statin initiation in accordance with clinical practice guidelines. We demonstrate that approaches that incorporate fairness considerations into the model training objective typically do not improve model performance or confer greater net benefit for any of the studied patient populations compared to the use of standard learning paradigms followed by threshold selection concordant with patient preferences, evidence of intervention effectiveness, and model calibration. These results hold when the measured outcomes are not subject to differential measurement error across patient populations and threshold selection is unconstrained, regardless of whether differences in model performance metrics, such as in true and false positive error rates, are present. In closing, we argue for focusing model development efforts on developing calibrated models that predict outcomes well for all patient populations while emphasizing that such efforts are complementary to transparent reporting, participatory design, and reasoning about the impact of model-informed interventions in context.