Internet of Things (IoT) is reshaping the incumbent industry to smart industry featured with data-driven decision-making. However, intrinsic features of IoT result in a number of challenges such as decentralization, poor interoperability, privacy and security vulnerabilities. Blockchain technology brings the opportunities in addressing the challenges of IoT. In this paper, we investigate the integration of blockchain technology with IoT. We name such synthesis of blockchain and IoT as Blockchain of Things (BCoT). This paper presents an in-depth survey of BCoT and discusses the insights of this new paradigm. In particular, we first briefly introduce IoT and discuss the challenges of IoT. Then we give an overview of blockchain technology. We next concentrate on introducing the convergence of blockchain and IoT and presenting the proposal of BCoT architecture. We further discuss the issues about using blockchain for 5G beyond in IoT as well as industrial applications of BCoT. Finally, we outline the open research directions in this promising area.