Programming trends suggest that software development will undergo a radical change in the future: the combination of machine learning, artificial intelligence, natural language processing, and code generation technologies will improve in such a way that machines, instead of humans, will write most of their own code by 2040. This poses a number of interesting challenges for scientific research, especially as the hardware on which this Machine Generated Code will run becomes extremely heterogeneous. Indeed, extreme heterogeneity may drive the creation of this technology because it will allow humans to cope with the difficulty of programming different devices efficiently and easily.