Aspects of frameworks, such as inversion of control and the structure of framework applications, require developers to adjust their debugging strategies as compared to debugging sequential programs. However, the benefits and challenges of framework debugging are not fully understood, and gaining this knowledge could provide guidance in debugging strategies and framework tool design. To gain insight into the process developers use to fix problems in framework applications, we performed two human studies investigating how developers fix applications that use a framework API incorrectly. These studies focused on the Android Fragment class and the ROS framework. We analyzed the results of the studies using a mixed-methods approach, consisting of techniques from grounded theory, qualitative content analysis, and case studies. From our analysis, we produced a theory of the benefits and challenges of framework debugging. This theory states that developers find inversion of control challenging when debugging but find the structure of framework applications helpful. This theory could be used to guide strategies for debugging framework applications and framework tool designs.