Communication-aware robot planning requires accurate predictions of wireless network performance. Current approaches rely on channel-level metrics such as received signal strength and signal-to-noise ratio, assuming these translate reliably into end-to-end throughput. We challenge this assumption through a measurement campaign in a private 5G industrial environment. We evaluate throughput predictions from a commercial ray-tracing simulator as well as data-driven Gaussian process regression models against measurements collected using a mobile robot. The study uses off-the-shelf user equipment in an underground, radio-shielded facility with detailed 3D modeling, representing a best-case scenario for prediction accuracy. The ray-tracing simulator captures the spatial structure of indoor propagation and predicts channel-level metrics with reasonable fidelity. However, it systematically over-predicts throughput, even in line-of-sight regions. The dominant error source is shown to be over-estimation of sustainable MIMO spatial layers: the simulator assumes near-uniform four-layer transmission while measurements reveal substantial adaptation between one and three layers. This mismatch inflates predicted throughput even when channel metrics appear accurate. In contrast, a Gaussian process model with a rational quadratic kernel achieves approximately two-thirds reduction in prediction error with near-zero bias by learning end-to-end throughput directly from measurements. These findings demonstrate that favorable channel conditions do not guarantee high throughput; communication-aware planners relying solely on channel-centric predictions risk overly optimistic trajectories that violate reliability requirements. Accurate throughput prediction for 5G systems requires either extensive calibration of link-layer models or data-driven approaches that capture real system behavior.