Semantic segmentation of LiDAR data presents considerable challenges, particularly when dealing with diverse sensor types and configurations. However, incorporating semantic information can significantly enhance the accuracy and robustness of LiDAR-based localization techniques for autonomous mobile systems. We propose an approach that integrates semantic camera data with LiDAR segmentation to address this challenge. By projecting LiDAR points into the semantic segmentation space of the camera, our method enhances the precision and reliability of the LiDAR-based localization pipeline. For validation, we utilize the CoCar NextGen platform from the FZI Research Center for Information Technology, which offers diverse sensor modalities and configurations. The sensor setup of CoCar NextGen enables a thorough analysis of different sensor types. Our evaluation leverages the state-of-the-art Depth-Anything network for camera image segmentation and an adaptive segmentation network for LiDAR segmentation. To establish a reliable ground truth for LiDAR-based localization, we make us of a Global Navigation Satellite System (GNSS) solution with Real-Time Kinematic corrections (RTK). Additionally, we conduct an extensive 55 km drive through the city of Karlsruhe, Germany, covering a variety of environments, including urban areas, multi-lane roads, and rural highways. This multimodal approach paves the way for more reliable and precise autonomous navigation systems, particularly in complex real-world environments.