Precise vehicle state estimation is crucial for safe and reliable autonomous driving. The number of measurable states and their precision offered by the onboard vehicle sensor system are often constrained by cost. For instance, measuring critical quantities such as the Vehicle Sideslip Angle (VSA) poses significant commercial challenges using current optical sensors. This paper addresses these limitations by focusing on the development of high-performance virtual sensors to enhance vehicle state estimation for active safety. The proposed Uncertainty-Aware Hybrid Learning (UAHL) architecture integrates a machine learning model with vehicle motion models to estimate VSA directly from onboard sensor data. A key aspect of the UAHL architecture is its focus on uncertainty quantification for individual model estimates and hybrid fusion. These mechanisms enable the dynamic weighting of uncertainty-aware predictions from machine learning and vehicle motion models to produce accurate and reliable hybrid VSA estimates. This work also presents a novel dataset named Real-world Vehicle State Estimation Dataset (ReV-StED), comprising synchronized measurements from advanced vehicle dynamic sensors. The experimental results demonstrate the superior performance of the proposed method for VSA estimation, highlighting UAHL as a promising architecture for advancing virtual sensors and enhancing active safety in autonomous vehicles.