The peak performance of any SpMV depends primarily on the available memory bandwidth and its effective use. GPUs, ASICs, and new FPGAs have higher and higher bandwidth; however, for large scale and highly sparse matrices, SpMV is still a hard problem because of its random access pattern and workload imbalance. Here, we show how to turn randomness to our advantage. We propose a matrix permutation pre-processing step that aims to maximize the entropy of the distribution of the nonzero elements. We seek any permutation that uniformly distributes the non-zero elements' distribution, thereby generating a SpMV problem that is amenable to work load balancing or to speed up sort algorithms. We conjecture these permutations would be most effective for matrices with no dense rows or columns and, as in preconditioning, when the matrix is reused. We shall show that entropy maximization is an optimization that any architecture may take advantage although in different ways. Most importantly, any developer can consider and deploy. We shall present cases where we can improve performance by 15\% on AMD-based (GPU-CPU) systems.