Human mobility simulation plays a crucial role in various real-world applications. Recently, to address the limitations of traditional data-driven approaches, researchers have explored leveraging the commonsense knowledge and reasoning capabilities of large language models (LLMs) to accelerate human mobility simulation. However, these methods suffer from several critical shortcomings, including inadequate modeling of urban spaces and poor integration with both individual mobility patterns and collective mobility distributions. To address these challenges, we propose \textbf{C}ityGPT-Powered \textbf{A}gentic framework for \textbf{M}obility \textbf{S}imulation (\textbf{CAMS}), an agentic framework that leverages the language based urban foundation model to simulate human mobility in urban space. \textbf{CAMS} comprises three core modules, including MobExtractor to extract template mobility patterns and synthesize new ones based on user profiles, GeoGenerator to generate anchor points considering collective knowledge and generate candidate urban geospatial knowledge using an enhanced version of CityGPT, TrajEnhancer to retrieve spatial knowledge based on mobility patterns and generate trajectories with real trajectory preference alignment via DPO. Experiments on real-world datasets show that \textbf{CAMS} achieves superior performance without relying on externally provided geospatial information. Moreover, by holistically modeling both individual mobility patterns and collective mobility constraints, \textbf{CAMS} generates more realistic and plausible trajectories. In general, \textbf{CAMS} establishes a new paradigm that integrates the agentic framework with urban-knowledgeable LLMs for human mobility simulation.