具体信息:

StackTrace    "   at MS.Internal.AppModel.ResourcePart.GetStreamCore(FileMode mode, FileAccess access)\r\n   at System.IO.Packaging.PackagePart.GetStream(FileMode mode, FileAccess access)\r\n   at System.IO.Packaging.PackagePart.GetStream()\r\n   at System.Windows.Application.LoadComponent(Object component, Uri resourceLocator)\r\n   at ecSolutions.EnquiryDefineTool.App.InitializeComponent() in d:\\2011-7-11ABC\\EnquiryDefineTool\\App.xaml:line 1\r\n   at ecSolutions.EnquiryDefineTool.App.Main() in D:\\2011-7-11ABC\\EnquiryDefineTool\\obj\\x86\\Debug\\App.g.cs:line 0\r\n   at System.AppDomain._nExecuteAssembly(RuntimeAssembly assembly, String[] args)\r\n   at System.AppDomain.ExecuteAssembly(String assemblyFile, Evidence assemblySecurity, String[] args)\r\n   at Microsoft.VisualStudio.HostingProcess.HostProc.RunUsersAssembly()\r\n   at System.Threading.ThreadHelper.ThreadStart_Context(Object state)\r\n   at System.Threading.ExecutionContext.Run(ExecutionContext executionContext, ContextCallback callback, Object state, Boolean ignoreSyncCtx)\r\n   at System.Threading.ExecutionContext.Run(ExecutionContext executionContext, ContextCallback callback, Object state)\r\n   at System.Threading.ThreadHelper.ThreadStart()"    string

解决方法：

查看：AssemblyInfo.cs 是否被屏蔽掉。
[assembly: NeutralResourcesLanguage("zh-cn", UltimateResourceFallbackLocation.Satellite)]

如果没有，将其屏蔽掉即可