General design principles for visualization have been relatively well-established based on a combination of cognitive and perceptual theory and empirical evaluations over the past 20 years. To determine how these principles hold up across use contexts and end-users, I argue that we should emphasize conceptual replication focused on determining practical significance and reducing methodological biases. This shift in thinking aims to determine how design principles interact with methodological approaches, laying the groundwork for visualization meta-science.