Human factors/ergonomics (HFE) standards are not only a useful reference for experienced HFE practitioners but can also provide guidance for organizations that are inexperienced in HFE design practice. HFE standards can give credibility to the value of introducing user centered methods. As computing technologies advance, knowledge of HFE has spread to the computing related work, and the field of human-computer interaction (HCI) has grown rapidly. Accordingly, HCI standards have evolved for guiding practice. There is great deal of literature concerned with the development and practice of international standards (e.g., International Organization for Standardization/ISO) and national (e.g., The American National Standards Institute/ANSI) HFE or HCI standards, but little on the practice of HCI standards at lower levels, such as at the level of enterprise. This chapter will focus on the practice of HCI standards there. It intends to assess the challenges of enterprise HCI standards from strategy, development, and governance perspectives. Specifically, we discuss the practices at Intel Corporation, a high-tech enterprise environment.