Combining clinical and omics data can improve both daily clinical routines and research to gain more insights into complex medical procedures. We present the results of our first phase in a multi-year collaboration with analysts and physicians aiming at improved inter-disciplinary biomarker identification. We also outline our user-centered approach along its challenges, describe the intermediate technical artifacts that serve as a basis for summative and formative evaluation for the second project phase. Finally, we sketch the road ahead and how we intend to combine visualization research with user-centered design through problem-based prioritization.