Scalable interactive visual data exploration is crucial in many domains due to increasingly large datasets generated at rapid rates. Details-on-demand provides a useful interaction paradigm for exploring large datasets, where users start at an overview, find regions of interest, zoom in to see detailed views, zoom out and then repeat. This paradigm is the primary user interaction mode of widely-used systems such as Google Maps, Aperture Tiles and ForeCache. These earlier systems, however, are highly customized with hardcoded visual representations and optimizations. A more general framework is needed to facilitate the development of visual data exploration systems at scale. In this paper, we present Kyrix, an end-to-end system for developing scalable details-on-demand data exploration applications. Kyrix provides developers with a declarative model for easy specification of general visualizations. Behind the scenes, Kyrix utilizes a suite of performance optimization techniques to achieve a response time within 500ms for various user interactions. We also report results from a performance study which shows that a novel dynamic fetching scheme adopted by Kyrix outperforms tile-based fetching used in earlier systems.