Equipment shortages in Africa undermine Science, Technology, Engineering and Mathematics (STEM) Education. We have pioneered the LabHackathon (LabHack): a novel initiative that adapts the conventional hackathon and draws on insights from the Open Hardware movement and Responsible Research and Innovation (RRI). LabHacks are fun, educational events that challenge student participants to build frugal and reproducible pieces of laboratory equipment. Completed designs are then made available to others. LabHacks can therefore facilitate the open and sustainable design of laboratory equipment, in situ, in Africa. In this case study we describe the LabHackathon model, discuss its application in a pilot event held in Zimbabwe and outline the opportunities and challenges it presents.