Virtual and Augmented Reality have the potential to change information work. The ability to modify the workers senses can transform everyday environments into a productive office, using portable head-mounted displays combined with conventional interaction devices, such as keyboards and tablets. While a stream of better, cheaper and lighter HMDs have been introduced for consumers in recent years, there are still many challenges to be addressed to allow this vision to become reality. This chapter summarizes the state of the art in the field of extended reality for knowledge work in everyday environments and proposes steps to address the open challenges.