We introduce a novel multimodal mobile database called HuMIdb (Human Mobile Interaction database) that comprises 14 mobile sensors acquired from 600 users. The heterogeneous flow of data generated during the interaction with the smartphones can be used to model human behavior when interacting with the technology. Based on this new dataset, we explore the capacity of smartphone sensors to improve bot detection. We propose a CAPTCHA method based on the analysis of the information obtained during a single drag and drop task. We evaluate the method generating fake samples synthesized with Generative Adversarial Neural Networks and handcrafted methods. Our results suggest the potential of mobile sensors to characterize the human behavior and develop a new generation of CAPTCHAs.