While in many graph mining applications it is crucial to handle a stream of updates efficiently in terms of {\em both} time and space, not much was known about achieving such type of algorithm. In this paper we study this issue for a problem which lies at the core of many graph mining applications called {\em densest subgraph problem}. We develop an algorithm that achieves time- and space-efficiency for this problem simultaneously. It is one of the first of its kind for graph problems to the best of our knowledge. In a graph $G = (V, E)$, the "density" of a subgraph induced by a subset of nodes $S \subseteq V$ is defined as $|E(S)|/|S|$, where $E(S)$ is the set of edges in $E$ with both endpoints in $S$. In the densest subgraph problem, the goal is to find a subset of nodes that maximizes the density of the corresponding induced subgraph. For any $ε>0$, we present a dynamic algorithm that, with high probability, maintains a $(4+ε)$-approximation to the densest subgraph problem under a sequence of edge insertions and deletions in a graph with $n$ nodes. It uses $\tilde O(n)$ space, and has an amortized update time of $\tilde O(1)$ and a query time of $\tilde O(1)$. Here, $\tilde O$ hides a $O(\poly\log_{1+ε} n)$ term. The approximation ratio can be improved to $(2+ε)$ at the cost of increasing the query time to $\tilde O(n)$. It can be extended to a $(2+ε)$-approximation sublinear-time algorithm and a distributed-streaming algorithm. Our algorithm is the first streaming algorithm that can maintain the densest subgraph in {\em one pass}. The previously best algorithm in this setting required $O(\log n)$ passes [Bahmani, Kumar and Vassilvitskii, VLDB'12]. The space required by our algorithm is tight up to a polylogarithmic factor.