We consider the $(\ell_p,\ell_r)$-Grothendieck problem, which seeks to maximize the bilinear form $y^T A x$ for an input matrix $A$ over vectors $x,y$ with $\|x\|_p=\|y\|_r=1$. The problem is equivalent to computing the $p \to r^*$ operator norm of $A$. The case $p=r=\infty$ corresponds to the classical Grothendieck problem. Our main result is an algorithm for arbitrary $p,r \ge 2$ with approximation ratio $(1+ε_0)/(\sinh^{-1}(1)\cdot γ_{p^*} \,γ_{r^*})$ for some fixed $ε_0 \le 0.00863$. Comparing this with Krivine's approximation ratio of $(π/2)/\sinh^{-1}(1)$ for the original Grothendieck problem, our guarantee is off from the best known hardness factor of $(γ_{p^*} γ_{r^*})^{-1}$ for the problem by a factor similar to Krivine's defect. Our approximation follows by bounding the value of the natural vector relaxation for the problem which is convex when $p,r \ge 2$. We give a generalization of random hyperplane rounding and relate the performance of this rounding to certain hypergeometric functions, which prescribe necessary transformations to the vector solution before the rounding is applied. Unlike Krivine's Rounding where the relevant hypergeometric function was $\arcsin$, we have to study a family of hypergeometric functions. The bulk of our technical work then involves methods from complex analysis to gain detailed information about the Taylor series coefficients of the inverses of these hypergeometric functions, which then dictate our approximation factor. Our result also implies improved bounds for "factorization through $\ell_{2}^{\,n}$" of operators from $\ell_{p}^{\,n}$ to $\ell_{q}^{\,m}$ (when $p\geq 2 \geq q$)--- such bounds are of significant interest in functional analysis and our work provides modest supplementary evidence for an intriguing parallel between factorizability, and constant-factor approximability.