We investigate a fundamental vertex-deletion problem called (Induced) Subgraph Hitting: given a graph $G$ and a set $\mathcal{F}$ of forbidden graphs, the goal is to compute a minimum-sized set $S$ of vertices of $G$ such that $G-S$ does not contain any graph in $\mathcal{F}$ as an (induced) subgraph. This is a generic problem that encompasses many well-known problems that were extensively studied on their own, particularly (but not only) from the perspectives of both approximation and parameterization. In this paper, we study the approximability of the problem on a large variety of graph classes. Our first result is a linear-time $(1+\varepsilon)$-approximation reduction from (Induced) Subgraph Hitting on any graph class $\mathcal{G}$ of bounded expansion to the same problem on bounded degree graphs within $\mathcal{G}$. This directly yields linear-size $(1+\varepsilon)$-approximation lossy kernels for the problems on any bounded-expansion graph classes. Our second result is a linear-time approximation scheme for (Induced) Subgraph Hitting on any graph class $\mathcal{G}$ of polynomial expansion, based on the local-search framework of Har-Peled and Quanrud [SICOMP 2017]. This approximation scheme can be applied to a more general family of problems that aim to hit all subgraphs satisfying a certain property $π$ that is efficiently testable and has bounded diameter. Both of our results have applications to Subgraph Hitting (not induced) on wide classes of geometric intersection graphs, resulting in linear-size lossy kernels and (near-)linear time approximation schemes for the problem.