Consider the following Online Boolean Matrix-Vector Multiplication problem: We are given an $n\times n$ matrix $M$ and will receive $n$ column-vectors of size $n$, denoted by $v_1,\ldots,v_n$, one by one. After seeing each vector $v_i$, we have to output the product $Mv_i$ before we can see the next vector. A naive algorithm can solve this problem using $O(n^3)$ time in total, and its running time can be slightly improved to $O(n^3/\log^2 n)$ [Williams SODA'07]. We show that a conjecture that there is no truly subcubic ($O(n^{3-ε})$) time algorithm for this problem can be used to exhibit the underlying polynomial time hardness shared by many dynamic problems. For a number of problems, such as subgraph connectivity, Pagh's problem, $d$-failure connectivity, decremental single-source shortest paths, and decremental transitive closure, this conjecture implies tight hardness results. Thus, proving or disproving this conjecture will be very interesting as it will either imply several tight unconditional lower bounds or break through a common barrier that blocks progress with these problems. This conjecture might also be considered as strong evidence against any further improvement for these problems since refuting it will imply a major breakthrough for combinatorial Boolean matrix multiplication and other long-standing problems if the term "combinatorial algorithms" is interpreted as "non-Strassen-like algorithms" [Ballard et al. SPAA'11]. The conjecture also leads to hardness results for problems that were previously based on diverse problems and conjectures, such as 3SUM, combinatorial Boolean matrix multiplication, triangle detection, and multiphase, thus providing a uniform way to prove polynomial hardness results for dynamic algorithms; some of the new proofs are also simpler or even become trivial. The conjecture also leads to stronger and new, non-trivial, hardness results.