惯性聚合 高效追踪和阅读你感兴趣的博客、新闻、科技资讯
阅读原文 在惯性聚合中打开

推荐订阅源

L
LangChain Blog
B
Blog RSS Feed
阮一峰的网络日志
阮一峰的网络日志
Cyber Security Advisories - MS-ISAC
Cyber Security Advisories - MS-ISAC
H
Help Net Security
MyScale Blog
MyScale Blog
WordPress大学
WordPress大学
Microsoft Azure Blog
Microsoft Azure Blog
GbyAI
GbyAI
小众软件
小众软件
大猫的无限游戏
大猫的无限游戏
Martin Fowler
Martin Fowler
Vercel News
Vercel News
S
SegmentFault 最新的问题
M
MIT News - Artificial intelligence
Microsoft Security Blog
Microsoft Security Blog
G
Google Developers Blog
Last Week in AI
Last Week in AI
Hugging Face - Blog
Hugging Face - Blog
酷 壳 – CoolShell
酷 壳 – CoolShell
博客园 - 【当耐特】
Google DeepMind News
Google DeepMind News
Engineering at Meta
Engineering at Meta
云风的 BLOG
云风的 BLOG

cs.DS updates on arXiv.org

PAC Learning with Bandit Feedback: Sharp Sample Complexity in the Realizable Setting Algorithms with Polynomially-Improved Approximation Factors for the $2 \rightarrow q$ Norm, and Applications A computational phase transition for learning-to-sample from Ising models Covering vertices by sequential stars Fermi-Dirac machines as quantizations of neurons A Comprehensive Evaluation of Vertex Elimination Algorithms for Algorithmic Differentiation A Tight Bound on Localization of Electrical Flows Optimal Dimension-Free Sampling for Regularized Classification Reducing the Randomness in Partition Oracles for Bounded Degree Minor-Free Graphs Beyond the Half-Approximation: Fair and Efficient Online Class Matching Efficient Uniform Sampling of Surjections via their Profiles Tractable Maximization of Budgeted Phylogenetic Diversity on Networks Utilizing Node Scanwidth Fairness in Aggregation: Optimal Top-$k$ and Improved Full Ranking Learning-Augmented Online Scheduling with Parsimonious Preemption Entropy Equivalence Testing Lumberjack: Better Differentially Private Random Forests through Heavy Hitter Detection in Trees The Secretary Problem with a Stochastic Precursor Polynomial-Time Robust Multiclass Linear Classification under Gaussian Marginals Efficient Banzhaf-Based Data Valuation for $k$-Nearest Neighbors Classification Block-Sphere Vector Quantization An Approximation Algorithm for Graph Label Selection Iterative Chow Filtering for Learning with Distribution Shift Complexity of Non-Log-Concave Sampling in Fisher Information Stochastic Matching via Local Sparsification Finite Sample Bounds for Learning with Score Matching What is Learnable in Valiant's Theory of the Learnable? Provable Quantization with Randomized Hadamard Transform Min-Max Optimization Requires Exponentially Many Queries Fast and Compact Graph Cuts for the Boykov-Kolmogorov Algorithm A proximal gradient algorithm for composite log-concave sampling
Meraculous2: fast accurate short-read assembly of large p...
Jarrod A. Chapman, Isaac Y. Ho, Eugene Goltsman, Daniel S. Rokhs · 2016-08-03 · via cs.DS updates on arXiv.org

We present Meraculous2, an update to the Meraculous short-read assembler that includes (1) handling of allelic variation using "bubble" structures within the de Bruijn graph, (2) improved gap closing, and (3) an improved scaffolding algorithm that produces more complete assemblies without compromising scaffolding accuracy. The speed and bandwidth efficiency of the new parallel implementation have also been substantially improved, allowing the assembly of a human genome to be accomplished in 24 hours on the JGI/NERSC Genepool system. To highlight the features of Meraculous2 we present here the assembly of the diploid human genome NA12878, and compare it with previously published assemblies of the same data using other algorithms. The Meraculous2 assemblies are shown to have better completeness, contiguity, and accuracy than other published assemblies for these data. Practical considerations including pre-assembly analyses of polymorphism and repetitiveness are described.