We’ve got ourselves a 10-game MLB DFS slate on Wednesday night, headlined by three fire-balling right-handed pitchers at the top of the pricing list. Do you go with Shohei Ohtani ($10,700), Jacob Misiorowski ($10,500) or Dylan Cease ($10,000)? Do you avoid all trio altogether?

Let’s break it all down and make some picks.

Make your DraftKings MLB DFS picks here: MLB $175K Bat Flip [$50K to 1st]

PITCHER

Stud

Jacob Misiorowski, Milwaukee Brewers vs. San Diego Padres, $10,500 – When I say that Misiorowski is in his own tier of pitcher, I’m referring to the fact that the sophomore currently owns the highest qualified strikeout rate in baseball (39.5%) and the lowest SIERA (2.40). It’s not particularly close, either. The guy is just out here mowing down opposing hitters with his 99th percentile average fastball velocity (99.5), which by the way, looks even faster due to his 100th percentile extension off the mound. Misiorowski is truly one of a kind. He’s also matchup proof, but it certainly doesn’t hurt his value that the Padres come into Wednesday’s action scuffling at the dish. To wit, San Diego is hitting .190 as a team in May with a 70 wRC+.

Value

Christian Scott, New York Mets vs. Detroit Tigers, $7,000 – I think we just have to ignore Scott’s first MLB start of 2026. The 26-year-old has really never struggled with command at any professional level, so it was very odd to see him walk half of the 10 batters he faced back on April 23. In the two outings since? Just three earned runs and two walks over 9.2 innings. He’s also struck out 14. That’s probably pretty important to mention. To put it plainly, Scott simply possesses a ton of upside for a pitcher with a price tag at just $7,000. He’s in a good matchup, too. Over the past two weeks, the Tigers rank 27th in ISO (.113), 26th in wRC+ (.83) and 25th in wOBA (.293). With Gleyber Torres (oblique) on the IL, only Riley Greene ($4,000) is hitting at the moment. It’s a great time to face Detroit.

INFIELD

Stud

Liam Hicks, Miami Marlins vs. Minnesota Twins, $5,400 – This might seem like an absurd price to pay for Hicks’ services, but this is what happens when you have more than twice as many home runs (9) as anyone else on your team. The Marlins are in a great spot on Wednesday, as Simeon Woods Richardson ($6,000) and his 6.92 ERA will toe the rubber for Minnesota. The left-handed Hicks has absolutely punished right-handed pitching in 2026, slashing .316/.377/.592 with a .276 ISO and a 163 wRC+ within the split. His overall 94th percentile expected batting average (.297) is pretty tantalizing, as well.

Value

Michael Busch, Chicago Cubs at Atlanta Braves, $4,000 – It was a slow start to the season for Busch, who did not hit his first home run until April 22. However, since that turning point, there’s been no looking back. In Busch’s past 19 games, the first baseman is slashing .309/.422/.559 with a .250 ISO and a 184 wRC+. The guy who hit 34 long balls in 2025 is looking like himself again, and I’d expect the good times to keep rolling with JR Ritchie ($7,500) on the mound for the Braves. The rookie has been allergic to LHBs in his three starts at the MLB level, surrendering 3.09 home runs per nine within the split, along with a .435 wOBA.

OUTFIELD

Stud

Corbin Carroll, Arizona Diamondbacks at Texas Rangers, $5,500 – While Kumar Rocker ($6,500) has pitched his best baseball at home this season, he’s still allowing opposing LHBs to hit .299 with a .376 wOBA. Well, Carroll is one of the best left-handed bats in the NL, so it makes sense to pay up for the former Rookie of the Year winner if you have the means. It also doesn’t hurt that Carroll went 30/30 in 2025. He has the ability to lift up your DFS lineup from the batter’s box and on the base paths. What a talent.

Value

Luke Raley, Seattle Mariners at Houston Astros, $3,400 – I’ll just say it: Luke Raley is playing more like a $5,400 DFS asset than one that’s priced at $3,400. The veteran outfielder is currently in possession of a 99th percentile barrel rate (22.2%) and a 97th percentile expected slugging rate (.601). Sure, his 36.6% strikeout rate is alarming, but you should be targeting players swinging from their heels in GPPs. We don’t need a singles hitter. It feels like Raley is almost guaranteed to do some damage tonight against Lance McCullers Jr. ($6,300). I mean, everyone else has been. McCullers sports a ghastly 9.39 ERA in his past five starts. Not ideal!