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DraftKings MLB Pick6 Fantasy Baseball Picks: Top Plays fo...
Blake Krass · 2026-05-08 · via DraftKings Network

Blake Krass shares his top fantasy baseball Pick6 picks and plays for the Friday MLB slate. Check ’em out here!

The MLB season is humming along. There are far more ways to get involved in the action than just via traditional betting. One of the more unique features on DraftKings this year is Pick6 Fantasy Baseball!

Here are my top Pick6 plays for today’s MLB slate.

DraftKings MLB Pick6 Plays

Juan Soto More Than 0.5 Total Bases (Promo Pick)

Juan Soto has been hitting the ball hard this season. He is one of 28 eligible batters in the MLB with an OPS over .900 this season. He also ranks in the top 20 in hard hit percentage. Over his last two games, he has a home run and a triple, showing what he can do with that power. Tonight, the Mets begin a series in Arizona, with Ryne Nelson taking the mound for the Diamondbacks. Nelson has a 6.61 ERA this season and has actually been much worse at home. Nelson has a 2.25 ERA on the road this season, but a shocking 14.40 ERA in Arizona. He already faced the Mets once this season, but that came when Soto was on the IL. Over his career, however, Soto has hit Nelson hard. In 12 career at-bats against Nelson, Soto has two home runs and a 1.443 OPS. Thanks to this great promo from DraftKings Pick6, you only need a base hit out of Soto for this pick to win. He should stay hot and record at least a base hit in this game against Nelson and the Diamondbacks.

Freddie Freeman More Than 1.5 Hits + Runs + RBIs

Freddie Freeman is looking like Freddie Freeman as of late. After a bit of a slow start to the season, by his standards, Freeman has been on fire ever since the calendar turned to May. In six games this month, Freeman is batting .375 with a .923 OPS. Freeman has at least one hit in all six of those games and has either scored a run or driven in a run in four of those six games. Freeman should keep his hot bat going against Chris Sale and the Braves. Sale has been excellent this season, but Freeman has had his number over the years. Freeman is 3/9 with a home run and two doubles in his career against Sale.

As great as Sale has been, he has not been quite as sharp on the road. His one awful start this season came on a West Coast trip to Los Angeles to face the Angels, where he gave up six runs. He is now back in Los Angeles and facing the best lineup in baseball. Sale has a 0.75 ERA in Atlanta this season, but a 4.00 ERA on the road. The Dodgers should be able to create some offense against Sale, with Freeman in particular hitting him hard to generate a run or two.

Jesus Luzardo More Than 8.5 Strikeouts

Jesus Luzardo should be in for a stellar performance against the Rockies on Friday night. Luzardo really struggled over his first couple of starts this season, but he is back to his best as of late. Over his last three starts, he has a 1.50 ERA. Despite giving up a lot of runs over his first couple of starts, Luzardo’s strikeout numbers have been excellent all season. He is averaging 11.3 K/9 this season, the fifth-best mark in baseball this season. Luzardo should keep those numbers going against the Rockies. Colorado is striking out at an astonishingly high rate against left-handed pitchers this season. The Rockies have a 29.7% K-percentage against lefties in 2026. That is the worst mark in all of baseball. Luzardo threw 10 strikeouts last time out against the Marlins and should replicate that performance at home against the Rockies.


What is DraftKings Pick6?

Pick6 is a peer-to-peer fantasy variant where you build a lineup (your “Pick Set”) of 2+ players and select whether or not you believe each will outperform their listed stat projection. Enter your Pick Set in Pick6 contests to compete against other users. Get enough picks correct and win a share of cash prizes.

How to Play

Create a Pick Set

Create a Pick Set by choosing 2+ players from the same sport and Pick Group (a set of picks available from a group of competitions). For each player, simply select if you think they’ll have more or less than their listed stat projection. In each Pick Set, you can not pick the same player twice, and you must pick players from at least two different teams.

Enter an Amount

Once you finalize your Pick Set, choose your entry fee amount. Your entries will be automatically distributed into available contests, subject to your confirmation.

Sweat Your Picks

When the games go live, use the My Picks tab to follow your picks in real time to track how your players are performing against their projections and how they stack up against other users.

Compete for Prizes

Make enough correct picks and win a share of the contests’ guaranteed prizes. Any prizes won will be credited to your DraftKings account after contests are finalized.


Play at DraftKings Pick6 or by downloading the DraftKings Pick6 app on Apple or Google!


Gambling Problem? Call 1-800-GAMBLER. Must be at least 18 years or older. Higher age limits may apply in some states. Eligibility restrictions apply. Valid only in states where DraftKings Pick6 operates. Void where prohibited. For entertainment purposes only. Winning a contest on DraftKings depends on knowledge and exercise of skill. See terms at pick6.draftkings.com.