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DraftKings Network

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DraftKings MLB Pick6 Fantasy Baseball Picks: Top Plays fo...
Blake Krass · 2026-05-16 · via DraftKings Network

Blake Krass shares his top fantasy baseball Pick6 picks and plays for the Friday MLB slate. Check ’em out here!

The MLB season is humming along. There are far more ways to get involved in the action than just via traditional betting. One of the more unique features on DraftKings this year is Pick6 Fantasy Baseball!

Here are my top Pick6 plays for today’s MLB slate.

DraftKings MLB Pick6 Plays

Nolan Arenado More Than 1.5 Total Bases

Nolan Arenado is having a solid first season in Arizona, batting .274 with a .781 OPS. Both figures would be his best since 2022 if maintained. Arenado is heading back to very familiar territory at Coors Field this weekend. He will start by taking on the left-handed Kyle Freeland on Friday night. Freeland has a 6.00 ERA and gave up three home runs in his most recent outing. Arenado is 5/10 with two extra-base hits in his career against Freeland. The Rockies have a 4.40 bullpen ERA this season, the 10th-worst in baseball. Arenado should record an extra-base hit in this return to Coors Field.

Taylor Ward More Than 1.5 Hits + Runs + RBIs

Taylor Ward has a solid .803 OPS this season. Ward has a favorable matchup against Zach Littell and the Nationals tonight. Littell has a 6.94 ERA this season and has been even worse at home. At Nationals Park, Littell has a 7.71 ERA this season. Taylor Ward has also crushed Zach Littell over the years. He is 4/8 with two home runs in his career against the right-hander. Ward and the Orioles should generate some runs against Littell to get him over this combined prop number. The Nationals also have a 4.81 bullpen ERA, the fourth-worst bullpen ERA this season. Ward has gone over this number in each of his last two games and should do so against Littell and the Nationals as well.

Pete Crow-Armstrong More Than 0.5 Hits

Pete Crow-Armstrong is not meeting his levels from his breakout 2025 season. In fact, dating back to the midpoint of the 2025 season, he has not been particularly strong. That being said, he should get a base hit against his cross-town rivals tonight. Sean Burke is on the bump for the White Sox tonight. Burke has been decent in 2026, but has been much worse against lefties, allowing a .714 OPS to left-handed hitters this season. PCA is 3/5 with two extra-base hits in his career against Burke. The White Sox also have a 4.46 bullpen ERA, the ninth-worst mark in baseball. Crow-Armstrong should register a hit in this one.


What is DraftKings Pick6?

Pick6 is a peer-to-peer fantasy variant where you build a lineup (your “Pick Set”) of 2+ players and select whether or not you believe each will outperform their listed stat projection. Enter your Pick Set in Pick6 contests to compete against other users. Get enough picks correct and win a share of cash prizes.

How to Play

Create a Pick Set

Create a Pick Set by choosing 2+ players from the same sport and Pick Group (a set of picks available from a group of competitions). For each player, simply select if you think they’ll have more or less than their listed stat projection. In each Pick Set, you can not pick the same player twice, and you must pick players from at least two different teams.

Enter an Amount

Once you finalize your Pick Set, choose your entry fee amount. Your entries will be automatically distributed into available contests, subject to your confirmation.

Sweat Your Picks

When the games go live, use the My Picks tab to follow your picks in real time to track how your players are performing against their projections and how they stack up against other users.

Compete for Prizes

Make enough correct picks and win a share of the contests’ guaranteed prizes. Any prizes won will be credited to your DraftKings account after contests are finalized.


Play at DraftKings Pick6 or by downloading the DraftKings Pick6 app on Apple or Google!


Gambling Problem? Call 1-800-GAMBLER. Must be at least 18 years or older. Higher age limits may apply in some states. Eligibility restrictions apply. Valid only in states where DraftKings Pick6 operates. Void where prohibited. For entertainment purposes only. Winning a contest on DraftKings depends on knowledge and exercise of skill. See terms at pick6.draftkings.com.