MLB best bets today: Top picks, player props and expert predictions for Wednesday’s slate, backed by DraftKings Network analysts.

Published May 20, 2026 9:58 AM EDT

PITTSBURGH, PENNSYLVANIA - MAY 15: Brandon Lowe #5 of the Pittsburgh Pirates hits a two-run home run during the third inning against the Philadelphia Phillies at PNC Park on May 15, 2026 in Pittsburgh, Pennsylvania. (Photo by Joe Sargent/Getty Images)

PITTSBURGH, PENNSYLVANIA - MAY 15: Brandon Lowe #5 of the Pittsburgh Pirates hits a two-run home run during the third inning against the Philadelphia Phillies at PNC Park on May 15, 2026 in Pittsburgh, Pennsylvania. (Photo by Joe Sargent/Getty Images)

Carbonatix Pre-Player Loader

Audio By Carbonatix

Get the best MLB picks today, including top bets, player props and predictions from the MLB Dugout Betting Group for Wednesday’s games.

Join the MLB Dugout Betting Group now!


For up-to-date MLB betting information and data, check out both the DraftKings Sportsbook betting splits page and the DraftKings Sportsbook player props page!


Tim Finnegan

Parlay:

Brandon Lowe 1+ Home Runs (at STL)

Mickey Moniak 1+ Home Runs (vs TEX)

Odds: +2837

Tail this bet by clicking the odds above!

Analysis:


Brendan O’Sullivan

Parlay:

CIN Reds Moneyline (at PHI)

MIN Twins Run Line -1.5 (vs HOU)

Odds: +414

Tail this bet by clicking the odds above!

Analysis:


Charlie Cummings

Same Game Parlay (SGP):

BAL Orioles at TB Rays

TB Rays Moneyline

OVER 8.5 Total Runs

Odds: +252

Tail this bet by clicking the odds above!

Analysis:


Julian Edlow

Straight Bet:

TEX Rangers OVER 2.5 Total Runs –– 1st 5 Innings (at COL)

Odds: -115

Tail this bet by clicking the odds above!

Analysis:


The Crown Is Yours: Sign up for DraftKings and experience the ultimate host for games and betting experiences!

Related Articles

Click to Play