MLB best bets today: Top picks, player props and expert predictions for Wednesday’s slate, backed by DraftKings Network analysts.
Published May 20, 2026 9:58 AM EDT

PITTSBURGH, PENNSYLVANIA - MAY 15: Brandon Lowe #5 of the Pittsburgh Pirates hits a two-run home run during the third inning against the Philadelphia Phillies at PNC Park on May 15, 2026 in Pittsburgh, Pennsylvania. (Photo by Joe Sargent/Getty Images)

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Get the best MLB picks today, including top bets, player props and predictions from the MLB Dugout Betting Group for Wednesday’s games.
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Tim Finnegan
Parlay:
Brandon Lowe 1+ Home Runs (at STL)
Mickey Moniak 1+ Home Runs (vs TEX)
Odds: +2837
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Analysis:

Brendan O’Sullivan
Parlay:
CIN Reds Moneyline (at PHI)
MIN Twins Run Line -1.5 (vs HOU)
Odds: +414
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Analysis:

Charlie Cummings
Same Game Parlay (SGP):
BAL Orioles at TB Rays
TB Rays Moneyline
OVER 8.5 Total Runs
Odds: +252
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Analysis:

Julian Edlow
Straight Bet:
TEX Rangers OVER 2.5 Total Runs –– 1st 5 Innings (at COL)
Odds: -115
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Analysis:

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