South Africa and the Democratic Republic of Congo (DRC) present a complex linguistic landscape with languages such as Zulu, Sepedi, Afrikaans, French, English, and Tshiluba (Ciluba), which creates unique challenges for AI-driven translation and sentiment analysis systems due to a lack of accurately labeled data. This study seeks to address these challenges by developing a multilingual lexicon designed for French and Tshiluba, now expanded to include translations in English, Afrikaans, Sepedi, and Zulu. The lexicon enhances cultural relevance in sentiment classification by integrating language-specific sentiment scores. A comprehensive testing corpus is created to support translation and sentiment analysis tasks, with machine learning models such as Random Forest, Support Vector Machine (SVM), Decision Trees, and Gaussian Naive Bayes (GNB) trained to predict sentiment across low resource languages (LRLs). Among them, the Random Forest model performed particularly well, capturing sentiment polarity and handling language-specific nuances effectively. Furthermore, Bidirectional Encoder Representations from Transformers (BERT), a Large Language Model (LLM), is applied to predict context-based sentiment with high accuracy, achieving 99% accuracy and 98% precision, outperforming other models. The BERT predictions were clarified using Explainable AI (XAI), improving transparency and fostering confidence in sentiment classification. Overall, findings demonstrate that the proposed lexicon and machine learning models significantly enhance translation and sentiment analysis for LRLs in South Africa and the DRC, laying a foundation for future AI models that support underrepresented languages, with applications across education, governance, and business in multilingual contexts.