Tracking a financial index boils down to replicating its trajectory of returns for a well-defined time span by investing in a weighted subset of the securities included in the benchmark. Picking the optimal combination of assets becomes a challenging NP-hard problem even for moderately large indices consisting of dozens or hundreds of assets, thereby requiring heuristic methods to find approximate solutions. Hybrid quantum-classical optimization with variational gate-based quantum circuits arises as a plausible method to improve performance of current schemes. In this work we introduce a heuristic pruning algorithm to find weighted combinations of assets subject to cardinality constraints. We further consider different strategies to respect such constraints and compare the performance of relevant quantum ansätze and classical optimizers through numerical simulations.