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Diffusion Models in Simulation-Based Inference: A Tutoria...
[Submitted on 22 Dec 2025 (v1), last revised 8 Jul 2026 (this ve · 2025-12-22 · via cs.LG updates on arXiv.org

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Abstract:Diffusion models have recently emerged as powerful learners for simulation-based inference (SBI), enabling fast and accurate estimation of latent parameters from simulated and real data. Their score-based formulation offers a flexible way to learn conditional or joint distributions over parameters and observations, thereby providing a versatile solution to various modeling problems. In this tutorial review, we synthesize recent developments on diffusion models for SBI, covering design choices for training, inference, and evaluation. We highlight opportunities created by various concepts such as guidance, score composition, flow matching, consistency models, and joint modeling. Furthermore, we discuss how efficiency and statistical accuracy are affected by noise schedules, parameterizations, and samplers. Finally, we illustrate these concepts with case studies across parameter dimensionalities, simulation budgets, and model types, and outline open questions for future research.

Submission history

From: Jonas Arruda [view email]
[v1] Mon, 22 Dec 2025 15:10:35 UTC (8,821 KB)
[v2] Thu, 29 Jan 2026 14:33:29 UTC (8,870 KB)
[v3] Wed, 8 Jul 2026 15:20:55 UTC (9,510 KB)