We propose and test the LLM Brain Rot Hypothesis: continual exposure to junk web text induces lasting cognitive decline in large language models (LLMs). To unveil junk effects, we designed a novel controlled experiment on real Twitter/X corpora, by constructing junk and reverse-controlled datasets via two orthogonal operationalizations: M1 (engagement degree) and M2 (semantic quality), with matched token scale and training operations across conditions. Compared to the control group, continual pre-training of 4 LLMs on the junk dataset causes non-trivial declines (Hedges' g>0.3) on reasoning, long-context understanding, safety, and inflating "dark traits" (e.g., psychopathy, narcissism). The gradual mixtures of junk and control datasets also yield dose-response cognition decay: for example, under M1, ARC-Challenge with Chain-of-Thought drops 72.1 -> 57.2 and RULER-CWE 83.7 -> 52.3 as junk ratio rises from 0% to 100%. Error forensics reveal several key insights. First, we identify thought-skipping as the primary lesion in reasoning: models increasingly truncate or skip chains. Second, partial but incomplete healing is observed: scaling instruction tuning and clean continual pre-training improve the declined cognition, yet cannot restore baseline capability, suggesting persistent representational drift rather than format mismatch. Finally, we discover that the popularity, a non-semantic metric, of a tweet is a better indicator of the Brain Rot effect than the length in M1. Together, the results provide significant, multi-perspective evidence that social effects of data could be a causal driver of LLM capability decay in continual pre-training, thereby motivating routine "cognitive health checks" for deployed and evolving LLMs.