Vision-language pre-training (VLP) models are vulnerable to adversarial examples, particularly in black-box scenarios. Existing multimodal attacks often suffer from limited perturbation diversity and unstable multi-stage pipelines. To address these challenges, we propose 2S-GDA, a two-stage globally-diverse attack framework. The proposed method first introduces textual perturbations through a globally-diverse strategy by combining candidate text expansion with globally-aware replacement. To enhance visual diversity, image-level perturbations are generated using multi-scale resizing and block-shuffle rotation. Extensive experiments on VLP models demonstrate that 2S-GDA consistently improves attack success rates over state-of-the-art methods, with gains of up to 11.17\% in black-box settings. Our framework is modular and can be easily combined with existing methods to further enhance adversarial transferability.