Urban public transport disruptions require rapid response strategies, yet existing studies rarely provide a decision support framework to compare alternative disruption response solutions using a common set of dynamic, passenger, operator, and environment oriented indicators. This paper proposes a KPI-driven, time-indexed framework to assess the resilience of disruption response solutions in urban transit systems. The framework combines an optimization model with a behavioral evaluation in agent-based simulation. It also underlays the secondary service degradation induced on helper lines when in-service vehicles are withdrawn to support the disrupted corridor. Rather than treating resilience as a single score, it evaluates complementary dimensions including vulnerability, adaptability, robustness, resilience loss, responsiveness, cost-based performance, emissions, and equity. The framework is implemented for the RER B transit line in the Ile-de-France (Paris) network. Results show that the coordinated strategy provides the most balanced resilience profile, combining high service continuity with lower total disruption cost than single mode alternatives, while also improving equity and maintaining competitive environmental performance. Sensitivity analysis further identifies the disruption conditions under which coordinated multimodal response is most valuable.